Safety evaluation of cricket(Gryllus bimaculatus) extract in Sprague-Dawley rats

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Thirteen-Week Oral Dose Toxicity Study of G. bimaculatus in Sprague-Dawley Rats

Gryllus bimaculatus (Gb) was orally administered at doses of 0, 0.04, 0.2, 1 and 5 g/kg bw/day for 13 consecutive weeks. There were no observed clinical signs or deaths related to treatment in all the groups tested. Therefore, the approximate lethal oral dose of G. bimaculatus was considered to be higher than 5 g/kg in rats. Throughout the administration period, no significant changes in diet c...

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ژورنال

عنوان ژورنال: International Journal of Industrial Entomology

سال: 2016

ISSN: 1598-3579

DOI: 10.7852/ijie.2016.32.1.12